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Hence, the metabolite is responsible for about 20% of sildenafil's motion. Sildenafil is excreted as metabolites predominantly during the feces (about eighty% of administered oral dose) and also to a lesser extent in the urine (all-around 13% on the administered oral dose). If taken with a superior-Extra fat meal, absorption is reduced; enough time taken to succeed in the maximum plasma concentration raises by all over a single hour, and the utmost concentration itself is lowered by almost one-3rd.[fifty two]
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In uno studio clinico di confronto tra tadalafil 5 mg somministrato insieme a finasteride five mg nel trattamento dei sintomi dell’iperplasia prostatica benigna, non sono state identificate nuove reazioni avverse.
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Prima di prendere in considerazione il trattamento farmacologico, devono essere effettuati un’anamnesi ed un esame obiettivo al wonderful di diagnosticare la disfunzione erettile e determinare le induce che possono essere alla base della patologia.
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